Tool Talk with Dynamic Biosensors

heliX Next-Generation Modular Biosensor for Interaction and Conformation Analysis

Presented by: Ulrich Rant, CEO, Dynamic Biosensors GmbH

WHERE AND WHEN

Wednesday, February 26th, 2020
10:00am–11:00am
12-0168, MIT.nano (basement level), Building 12
60 Vassar Street (rear)
Cambridge, MA

REGISTER

switchSENSE® is a novel molecular interaction technology that employs electrically switchable DNA surfaces for the measurement of high sensitivity binding kinetics and target structural measurements. 

  • The seminar will highlight the broad range of the switchSENSE® technology applications supported by the recently launched heliX® biosensor: 
  • Size and Conformational Change | Screening and ranking of small molecule induced conformational changes by de novo real-time conformation referencing 
  • Bispecific Antibodies | Bifunctional sensor functionalization, advanced ligand density control and two-color fluorescence detection for the in-depth analysis of bispecific binders. 
  • Resolving the fastest kinetics with confidence using advanced microfluidics and 10 ms data collection. 
  • DNA/RNA Binding Proteins | Flexible exchange of DNA/RNA targets for binding and enzymatic activity studies in real-time. 
  • From Small Molecules to Cells | Chip functionalization solutions for the biophysical characterization of very small or very large structures.

For further information, please contact Prof. Mark Bathe (mbathe@mit.edu) or Joanna Deek (deek@dynamic-biosensors.com